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Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons

The prefrontal cortex (PFC) plays a critical role in curbing impulsive behavior, but the underlying circuit mechanism remains incompletely understood. Here we show that a subset of dorsomedial PFC (dmPFC) layer 5 pyramidal neurons, which project to the subthalamic nucleus (STN) of the basal ganglia,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Bing, Nguyen, Thao Phuong, Ma, Chenyan, Dan, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382266/
https://ncbi.nlm.nih.gov/pubmed/32631999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000523117
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