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Impaired estrogen signaling underlies regulatory T cell loss-of-function in the chronically inflamed intestine
Signaling of 17β-estradiol (estrogen) through its two nuclear receptors, α and β (ERα, ERβ), is an important mechanism of transcriptional regulation. Although ERs are broadly expressed by cells of the immune system, the mechanisms by which they modulate immune responses remain poorly understood. ERβ...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7382259/ https://ncbi.nlm.nih.gov/pubmed/32632016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002266117 |
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