Detection of genes mutations in cerebrospinal fluid circulating tumor DNA from neoplastic meningitis patients using next generation sequencing

BACKGROUND: This study profiled the somatic genes mutations and the copy number variations (CNVs) in cerebrospinal fluid (CSF)-circulating tumor DNA (ctDNA) from patients with neoplastic meningitis (NM). METHODS: A total of 62 CSF ctDNA samples were collected from 58 NM patients for the next generat...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Zhao, Yue, He, Jun Ying, Cui, Jun Zhao, Meng, Zi-Qi, Zou, Yue Li, Guo, Xiao Su, Chen, Xin, Wang, Xueliang, Yan, Li-Tian, Han, Wei Xin, Li, Chunyan, Guo, Li, Bu, Hui
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382072/
https://ncbi.nlm.nih.gov/pubmed/32711494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07172-x
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