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The Regulating Mechanism of Chrysophanol on Protein Level of CaM-CaMKIV to Protect PC12 Cells Against Aβ(25-35)-Induced Damage
OBJECTIVE: To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ(25-35), and the involved mechanism. METHODS: After the establishment of an AD cell model induced by Aβ(25-35), the cell survival rate was detected by MTT, cell apoptosis was assayed by Hoechst 33342 st...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7381772/ https://ncbi.nlm.nih.gov/pubmed/32764873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S245128 |
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