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RNA helicase p68 inhibits the transcription and post-transcription of Pkd1 in ADPKD

Background: Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of the PKD1 and PKD2 genes. Dysregulation of the expression of PKD genes, the abnormal activation of PKD associated signaling pathways, and the expression and maturation of miRNAs regulates cyst progression. Howe...

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發表在:Theranostics
Main Authors: Zhang, Lu, Li, Linda Xiaoyan, Zhou, Julie Xia, Harris, Peter C., Calvet, James P., Li, Xiaogang
格式: Artigo
語言:Inglês
出版: Ivyspring International Publisher 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381742/
https://ncbi.nlm.nih.gov/pubmed/32724471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47315
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