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A new class of PentixaFor- and PentixaTher-based theranostic agents with enhanced CXCR4-targeting efficiency

Non-invasive PET imaging of CXCR4 expression in cancer and inflammation as well as CXCR4-targeted radioligand therapy (RLT) have recently found their way into clinical research by the development of the theranostic agents [(68)Ga]PentixaFor (cyclo(D-Tyr(1)-D-[NMe]Orn(2)(AMBS-[(68)Ga]DOTA)-Arg(3)-Nal...

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Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Osl, Theresa, Schmidt, Alexander, Schwaiger, Markus, Schottelius, Margret, Wester, Hans-Jürgen
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381729/
https://ncbi.nlm.nih.gov/pubmed/32724470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45537
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