Targeting the Notch and TGF-β signaling pathways to prevent retinal fibrosis in vitro and in vivo

Rationale: The Notch and transforming growth factor-β (TGFβ) signaling pathways are two intracellular mechanisms that control fibrosis in general but whether they play a major role in retinal fibrosis is less clear. Here we study how these two signaling pathways regulate Müller cell-dominated retina...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Fan, Jiawen, Shen, Weiyong, Lee, So-Ra, Mathai, Ashish Easow, Zhang, Rui, Xu, Gezhi, Gillies, Mark C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381727/
https://ncbi.nlm.nih.gov/pubmed/32724452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45192
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