Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

Hippocampal Lewy body pathology (LBP) is associated with changes in neurotrophic factor signaling and neuronal energy metabolism. LBP progression is attributed to the aggregation of α-synuclein (α-Syn) and its cell-to-cell transmission via extracellular vehicles (EVs). We recently discovered an enha...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Kumar, Rohit, Donakonda, Sainitin, Müller, Stephan A., Lichtenthaler, Stefan F., Bötzel, Kai, Höglinger, Günter U., Koeglsperger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381695/
https://ncbi.nlm.nih.gov/pubmed/32707433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101349
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