Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

Hippocampal Lewy body pathology (LBP) is associated with changes in neurotrophic factor signaling and neuronal energy metabolism. LBP progression is attributed to the aggregation of α-synuclein (α-Syn) and its cell-to-cell transmission via extracellular vehicles (EVs). We recently discovered an enha...

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Pubblicato in:iScience
Autori principali: Kumar, Rohit, Donakonda, Sainitin, Müller, Stephan A., Lichtenthaler, Stefan F., Bötzel, Kai, Höglinger, Günter U., Koeglsperger, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381695/
https://ncbi.nlm.nih.gov/pubmed/32707433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101349
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