Structural basis of RNA cap modification by SARS-CoV-2

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused millions of infections worldwide. In SARS coronaviruses, the non-structural protein 16 (nsp16), in conjunction with nsp10, methylates the 5′-end of virally encoded mRNAs to mimic cel...

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Udgivet i:Nat Commun
Main Authors: Viswanathan, Thiruselvam, Arya, Shailee, Chan, Siu-Hong, Qi, Shan, Dai, Nan, Misra, Anurag, Park, Jun-Gyu, Oladunni, Fatai, Kovalskyy, Dmytro, Hromas, Robert A., Martinez-Sobrido, Luis, Gupta, Yogesh K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381649/
https://ncbi.nlm.nih.gov/pubmed/32709886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17496-8
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