Landscape of circulating tumour DNA in metastatic breast cancer

BACKGROUND: We describe the genomic landscape of circulating tumour DNA (ctDNA) across pathological subtypes of metastatic breast cancer. METHODS: 255 clinically annotated patients with ctDNA testing by Guardant360 were stratified into HR+, HER2+, and TNBC cohorts. Frequency and heterogeneity of alt...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Davis, Andrew A., Jacob, Saya, Gerratana, Lorenzo, Shah, Ami N., Wehbe, Firas, Katam, Neelima, Zhang, Qiang, Flaum, Lisa, Siziopikou, Kalliopi P., Platanias, Leonidas C., Gradishar, William J., Behdad, Amir, Cristofanilli, Massimo
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381501/
https://ncbi.nlm.nih.gov/pubmed/32707446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102914
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