miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

Genomic amplification of 3q26.2 locus leads to the increased expression of microRNA 551b-3p (miR551b-3p) in triple-negative breast cancer (TNBC). Our results demonstrate that miR551b-3p translocates to the nucleus with the aid of importin-8 (IPO8) and activates STAT3 transcription. As a consequence,...

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Publicado en:Cell Rep
Autores principales: Parashar, Deepak, Geethadevi, Anjali, Aure, Miriam Ragle, Mishra, Jyotsna, George, Jasmine, Chen, Changliang, Mishra, Manoj K., Tahiri, Andliena, Zhao, Wei, Nair, Bindu, Lu, Yiling, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Camara, Amadou K.S., Liang, Mingyu, Rader, Janet S., Ramchandran, Ramani, You, Ming, Sood, Anil K., Kristensen, Vessela N., Mills, Gordon B., Pradeep, Sunila, Chaluvally-Raghavan, Pradeep
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380555/
https://ncbi.nlm.nih.gov/pubmed/31875548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.085
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