Are Epithelial Ovarian Cancers of the Mesenchymal Subtype Actually Intraperitoneal Metastases to the Ovary?

Primary ovarian high-grade serous carcinoma (HGSC) has been classified into 4 molecular subtypes: Immunoreactive, Proliferative, Differentiated, and Mesenchymal (Mes), of which the Mes subtype (Mes-HGSC) is associated with the worst clinical outcomes. We propose that Mes-HGSC comprise clusters of ca...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Hu, Ye, Taylor-Harding, Barbie, Raz, Yael, Haro, Marcela, Recouvreux, Maria Sol, Taylan, Enes, Lester, Jenny, Millstein, Joshua, Walts, Ann E., Karlan, Beth Y., Orsulic, Sandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380132/
https://ncbi.nlm.nih.gov/pubmed/32766252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00647
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