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Endotracheal intubation results in acute tracheal damage induced by mtDNA/TLR9/NF‐κB activity

Tracheitis secondary to placement of an endotracheal tube (ETT) is characterized by neutrophil accumulation in the tracheal lumen, which is generally associated with epithelial damage. Mitochondrial DNA (mtDNA), has been implicated in systemic inflammation and organ dysfunction following trauma; how...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Puyo, Carlos A., Earhart, Alexander, Staten, Nicholas, Prince, Oliver A., Haug, Colleen, Kollef, Marin, Awad, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379990/
https://ncbi.nlm.nih.gov/pubmed/30548974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5A0718-254RR
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