Intramuscular Diphenhydramine Does Not Affect Acute Doxorubicin Infusion-Related Arrhythmia Number or Severity in a Prospective Crossover Study in Canine Lymphoma: A Pilot Study

Background: Doxorubicin (DOX) is one of the most effective chemotherapeutics for canine high-grade lymphoma. In addition to dose-dependent chronic cardiotoxicity, DOX can trigger acute cardiac arrhythmias during drug infusion. Diphenhydramine premedication is commonly used, as histamine release is a...

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Detalhes bibliográficos
Publicado no:Front Vet Sci
Main Authors: Willcox, Jennifer Lindley, Belanger, Catherine, Burton, Jenna Hart, Yu, Lydia, Ueda, Yu, Visser, Lance C., Skorupski, Katherine, Stern, Joshua A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Veterinary Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379900/
https://ncbi.nlm.nih.gov/pubmed/32766291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2020.00368
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