Exosomes Secreted From Bone Marrow Mesenchymal Stem Cells Attenuate Oxygen-Glucose Deprivation/Reoxygenation-Induced Pyroptosis in PC12 Cells by Promoting AMPK-Dependent Autophagic Flux

Background: Cerebral ischemia–reperfusion (I/R) injury can lead to severe dysfunction, and its treatment is difficult. It is reported that nucleotide-binding domain and leucine-rich repeat family protein 3 (NLRP3) inflammasome-mediated cell pyroptosis is an important part of cerebral I/R injury and...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Zeng, Qing, Zhou, Yuqing, Liang, Donghui, He, He, Liu, Xiaoli, Zhu, Rui, Zhang, Meimei, Luo, Xun, Wang, Yao, Huang, Guozhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cellular Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379865/
https://ncbi.nlm.nih.gov/pubmed/32765221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00182
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