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Patients with congenital ichthyosis and TGM1 mutations overexpress other ARCI genes in the skin: Part of a barrier repair response?

Autosomal recessive congenital ichthyosis (ARCI) is a group of monogenic skin disorders caused by mutations in any of at least 12 different genes, many of which are involved in the epidermal synthesis of ω‐O‐acylceramides (acylCer). AcylCer are essential precursors of the corneocyte lipid envelope c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Dermatol
Hauptverfasser: Zhang, Hanqian, Ericsson, Maja, Weström, Simone, Vahlquist, Anders, Virtanen, Marie, Törmä, Hans
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379499/
https://ncbi.nlm.nih.gov/pubmed/30372788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13813
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