Anti-malarial Drugs Reduce Vascular Smooth Muscle Cell Proliferation via Activation of AMPK and Inhibition of Smad3 Signaling

OBJECTIVE: The aim of this study was to investigate the effects of 2 anti-malarial drugs, chloroquine (CQ) and hydroxychloroquine (HCQ), on inhibition of vascular smooth muscle cell (VSMC) proliferation both in vivo and in vitro via Adenosine monophosphate-activated protein kinase (AMPK) activation....

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Veröffentlicht in:J Lipid Atheroscler
Hauptverfasser: Lee, Heejung, Han, Jung-Hwa, Kim, Sujin, Kim, Suji, Cho, Du-Hyong, Woo, Chang-Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Lipidology and Atherosclerosis 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379117/
https://ncbi.nlm.nih.gov/pubmed/32821717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12997/jla.2019.8.2.267
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