Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen causing a febrile illness in humans, which can progress to hemorrhagic manifestations, multi-organ failure, and death. Current mouse models of CCHFV infection reliably succumb to virus challenge but vary in their ability to refle...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ranadheera, Charlene, Valcourt, Emelissa J., Warner, Bryce M., Poliquin, Guillaume, Rosenke, Kyle, Frost, Kathy, Tierney, Kevin, Saturday, Greg, Miao, Jinxin, Westover, Jonna B., Gowen, Brian B., Booth, Stephanie, Feldmann, Heinz, Wang, Zhongde, Safronetz, David
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378551/
https://ncbi.nlm.nih.gov/pubmed/32704046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69054-3
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