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Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors

Zeta inhibitory peptide (ZIP), a PKMζ inhibitor, is widely used to interfere with the maintenance of acquired memories. ZIP is able to erase memory even in the absence of PKMζ, via an unknown mechanism. We found that ZIP induces redistribution of the AMPARGluA1 in HEK293 cells and primary cortical n...

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書目詳細資料
發表在:Nat Commun
Main Authors: Bingor, Alexey, Haham, Tomer, Thornton, Claire, Stern-Bach, Yael, Yaka, Rami
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378180/
https://ncbi.nlm.nih.gov/pubmed/32703948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17484-y
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