IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma

The clinical features of EBV-positive diffuse large B cell lymphoma (DLBCL) indicate a poorer prognosis than EBV-negative DLBCL. Currently, there is no efficacious drug for EBV-positive DLBCL. The cytokine interleukin-21 (IL-21) has been reported to be pro-apoptotic in DLBCL cell lines and is being...

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Pubblicato in:Sci Rep
Autori principali: Wang, Yuxuan, Wang, Chengcheng, Cai, Xiyunyi, Mou, Chang, Cui, Xueting, Zhang, Yingying, Ge, Feng, Dong, Hao, Hao, Yuanyuan, Cai, Lei, Wu, Shuting, Feng, Chenjie, Chen, Jiamin, Li, Jianyong, Xu, Wei, Fan, Lei, Xie, Weijia, Tong, Yue, Gu, Harvest Feng, Wu, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378064/
https://ncbi.nlm.nih.gov/pubmed/32704112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69227-0
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