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MiR130b from Schlafen4(+) MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer

The myeloid differentiation factor Schlafen4 (Slfn4) marks a subset of myeloid-derived suppressor cells (MDSCs) in the stomach during Helicobacter-induced spasmolytic polypeptide-expressing metaplasia (SPEM). OBJECTIVE: To identify the gene products expressed by Slfn4(+)-MDSCs and to determine how t...

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Bibliographic Details
Published in:Gut
Main Authors: Ding, Lin, Li, Qian, Chakrabarti, Jayati, Munoz, Andres, Faure-Kumar, Emmanuelle, Ocadiz-Ruiz, Ramon, Razumilava, Nataliya, Zhang, Guiying, Hayes, Michael H, Sontz, Ricky A, Mendoza, Zoe Elena, Mahurkar, Swapna, Greenson, Joel K, Perez-Perez, Guillermo, Hanh, Nguyen Thi Hong, Zavros, Yana, Samuelson, Linda C, Iliopoulos, Dimitrios, Merchant, Juanita L
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377952/
https://ncbi.nlm.nih.gov/pubmed/31980446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-318817
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