Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment

Synaptic neurodegeneration of retinal ganglion cells (RGCs) is the earliest event in the pathogenesis of diabetic retinopathy. Our previous study proposed that impairment of mitochondrial trafficking by hyperphosphorylated tau is a potential contributor to RGCs synapse degeneration. However, other m...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Shu, Xing-Sheng, Zhu, Huazhang, Huang, Xiaoyan, Yang, Yangfan, Wang, Dandan, Zhang, Yiling, Zhang, Weizhen, Ying, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377872/
https://ncbi.nlm.nih.gov/pubmed/32575075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103446
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