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PAK4 suppresses TNF-induced release of endothelial microparticles in HUVECs cells

Tumor necrosis factor-α (TNF) is a pro-inflammatory cytokine upregulated in many inflammatory diseases, and a potent inducer of endothelial cell-derived microparticle (EMP) formation. In this study, we identified the protein kinase PAK4 as a key regulator of the TNF-induced EMP release from human um...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Shouqin, Yin, Yingjie, Li, Congye, Zhao, Yi, Wang, Qixing, Zhang, Xiangyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377857/
https://ncbi.nlm.nih.gov/pubmed/32657762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103173
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