HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

Type-2 immunity elicits tissue repair and homeostasis, however dysregulated type-2 responses cause aberrant tissue remodelling, as observed in asthma. Severe respiratory viral infections in infancy predispose to later asthma, however, the processes that mediate tissue damage-induced type-2 inflammat...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Loh, Zhixuan, Simpson, Jennifer, Ullah, Ashik, Zhang, Vivian, Gan, Wan J., Lynch, Jason P., Werder, Rhiannon B., Sikder, Al Amin, Lane, Katie, Sim, Choon Boon, Porrello, Enzo, Mazzone, Stuart B., Sly, Peter D., Steptoe, Raymond J., Spann, Kirsten M., Sukkar, Maria B., Upham, John W., Phipps, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377495/
https://ncbi.nlm.nih.gov/pubmed/32658914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008651
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