Vagus nerve stimulation reduces spreading depolarization burden and cortical infarct volume in a rat model of stroke

Cortical spreading depolarization (SD) waves negatively affect neuronal survival and outcome after ischemic stroke. We here aimed to investigate the effects of vagus nerve stimulation (VNS) on SDs in a rat model of focal ischemia. To this end, we delivered non-invasive VNS (nVNS) or invasive VNS (iV...

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Udgivet i:PLoS One
Main Authors: Lindemann, Jan, Rakers, Cordula, Matuskova, Hana, Simon, Bruce J., Kinfe, Thomas, Petzold, Gabor C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377493/
https://ncbi.nlm.nih.gov/pubmed/32702055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236444
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