Most Non Invasive Prenatal Screens Failing Due to Inadequate Fetal Cell Free DNA are Negative for Trisomy when Repeated

OBJECTIVE: We aimed to test for an association between the amount of circulating fetal cell-free DNA and trisomy, and whether NIPS failure due to low fetal fraction indicates trisomy risk. METHOD: Maternal BMI, maternal age, fetal sex, gestational age, fetal cfDNA fraction, and NIPS results was coll...

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Vydáno v:Prenat Diagn
Hlavní autoři: Lopes, Jaime L., Lopes, Guilherme S., Enninga, Elizabeth Ann L., Kearney, Hutton M., Hoppman, Nicole L., Rowsey, Ross A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377435/
https://ncbi.nlm.nih.gov/pubmed/32274800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pd.5693
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