RNAi-mediated IARS2 knockdown inhibits proliferation and promotes apoptosis in human melanoma A375 cells

IARS2, which encodes the mitochondrial form of isoleucyl-tRNA synthetase, has been found to play an important role in a range of diseases, including cancer. However, the relationship between IARS2 and melanoma is still unclear. To evaluate the role of IARS2 in melanoma, we constructed a stable A375...

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Publicat a:Oncol Lett
Autors principals: Ma, Dongmei, Li, Song, Nie, Xiaojuan, Chen, Lamei, Chen, Nan, Hou, Dongsheng, Liu, Xiuhong, Gao, Binbin
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2020
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377047/
https://ncbi.nlm.nih.gov/pubmed/32724348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11688
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