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Rationale for Timely Insulin Therapy in Type 2 Diabetes Within the Framework of Individualised Treatment: 2020 Update

Type 2 diabetes is characterised by chronic hyperglycaemia and variable degrees of insulin deficiency and resistance. Hyperglycaemia and elevated fatty acids exert harmful effects on β-cell function, regeneration and apoptosis (gluco-lipotoxicity). Furthermore, chronic hyperglycaemia triggers a vici...

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Detalhes bibliográficos
Publicado no:Diabetes Ther
Main Authors: Hanefeld, Markolf, Fleischmann, Holger, Siegmund, Thorsten, Seufert, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376805/
https://ncbi.nlm.nih.gov/pubmed/32564335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13300-020-00855-5
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