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Next-generation sequencing analysis of each blastomere in good-quality embryos: insights into the origins and mechanisms of embryonic aneuploidy in cleavage-stage embryos

PURPOSE: To explore the whole-chromosome status, origins, and mechanisms of chromosomal abnormalities in good-quality cleavage embryos using multiple annealing and looping-based amplification cycle (MALBAC) sequencing. METHODS: The embryos studied came from7 patients (maternal aged 26–35) who had he...

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Bibliografski detalji
Izdano u:J Assist Reprod Genet
Glavni autori: Shi, Qiuwen, Qiu, Ying, Xu, Changlong, Yang, Hua, Li, Chunyuan, Li, Nina, Gao, Yumei, Yu, Caiyun
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376776/
https://ncbi.nlm.nih.gov/pubmed/32445153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01803-9
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