Astaxanthin alleviates spinal cord ischemia-reperfusion injury via activation of PI3K/Akt/GSK-3β pathway in rats

BACKGROUND: Ischemia-reperfusion injury of the spinal cord (SCII) often leads to unalterable neurological deficits, which may be associated with apoptosis induced by oxidative stress and inflammation. Astaxanthin (AST) is a strong antioxidant and anti-inflammatory agent with multitarget neuroprotect...

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Vydáno v:J Orthop Surg Res
Hlavní autoři: Fu, Jian, Sun, Haibin, Wei, Haofei, Dong, Mingjie, Zhang, Yongzhe, Xu, Wei, Fang, Yanwei, Zhao, Jianhui
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376638/
https://ncbi.nlm.nih.gov/pubmed/32703256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-01790-8
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