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MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice

A large number of hepatic functions are regulated by the circadian clock and recent evidence suggests that clock disruption could be a risk factor for liver complications. The circadian transcription factor Krüppel like factor 10 (KLF10) has been involved in liver metabolism as well as cellular infl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leclère, Pierre S., Rousseau, Déborah, Patouraux, Stéphanie, Guérin, Sophie, Bonnafous, Stéphanie, Gréchez-Cassiau, Aline, Ruberto, Anthony A., Luci, Carmelo, Subramaniam, Malayannan, Tran, Albert, Delaunay, Franck, Gual, Philippe, Teboul, Michèle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376252/
https://ncbi.nlm.nih.gov/pubmed/32699233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69085-w
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