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Ubiquitination and deubiquitination of MCL1 in cancer: deciphering chemoresistance mechanisms and providing potential therapeutic options

MCL1 is an important antiapoptotic member of the BCL-2 family that is distinguishable from other family members based on its relatively short half-life. Emerging studies have revealed the crucial role of MCL1 in the chemoresistance of cancer cells. The antiapoptotic function of MCL1 makes it a popul...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wu, Xiaowei, Luo, Qingyu, Liu, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376237/
https://ncbi.nlm.nih.gov/pubmed/32699213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02760-y
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