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DNA damage and antioxidant properties of CORM-2 in normal and cancer cells

In this study, we compared the effect of tricarbonyldichlororuthenium (II) dimer (CORM-2) and its CO-depleted molecule (iCORM-2) on human peripheral blood mononuclear cells (PBMCs) and human promyelocytic leukemia HL-60 cells. We determined cell viability, DNA damage and DNA repair kinetics. We also...

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Publicado en:Sci Rep
Autores principales: Juszczak, Michał, Kluska, Magdalena, Wysokiński, Daniel, Woźniak, Katarzyna
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376213/
https://ncbi.nlm.nih.gov/pubmed/32699258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68948-6
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