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Stress and behavioral correlates in the head-fixed method: stress measurements, habituation dynamics, locomotion, and motor-skill learning in mice

Manual restriction of head movement, or head-fixation, of awake rodents allows for sophisticated investigation of neural circuits in vivo, that would otherwise be impossible in completely freely moving animals. While it is known that head-fixation induces stress, the scale of this stress and habitua...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Juczewski, Konrad, Koussa, Jonathan A., Kesner, Andrew J., Lee, Jeong O., Lovinger, David M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376196/
https://ncbi.nlm.nih.gov/pubmed/32699235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69132-6
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