Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations

Ferritin is an iron-binding molecule, which comprises 24 subunits, heavy (FeH) and light (FeL) subunits, suggested to have a pathogenic role by the ‘hyperferritinemic syndrome’. In this work, we tested (1) FeH and FeL in bone marrow (BM) and sera in patients with macrophage activation syndrome (MAS)...

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Vydáno v:Sci Rep
Hlavní autoři: Ruscitti, Piero, Di Benedetto, Paola, Berardicurti, Onorina, Panzera, Noemi, Grazia, Nicolò, Lizzi, Anna Rita, Cipriani, Paola, Shoenfeld, Yehuda, Giacomelli, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376151/
https://ncbi.nlm.nih.gov/pubmed/32699419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69031-w
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