Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains

This study demonstrates a role for the extracellular matrix protein nephronectin (NPNT) in promoting experimental breast cancer brain metastasis, possibly through enhanced binding to- and migration through brain endothelial cells. With the introduction of more targeted breast cancer treatments, a pr...

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發表在:Sci Rep
Main Authors: Magnussen, Synnøve Norvoll, Toraskar, Jimita, Wilhelm, Imola, Hasko, Janos, Figenschau, Stine Linn, Molnar, Judit, Seppola, Marit, Steigen, Sonja E., Steigedal, Tonje S., Hadler-Olsen, Elin, Krizbai, Istvan A., Svineng, Gunbjørg
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376038/
https://ncbi.nlm.nih.gov/pubmed/32699247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69242-1
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