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The role and function of IκKα/β in monocyte impairment

Following major trauma, sepsis or surgery, some patients exhibit an impaired monocyte inflammatory response that is characterized by a decreased response to a subsequent bacterial challenge. To investigate this poorly understood phenomenon, we adopted an in-vitro model of endotoxin tolerance utilisi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Galbraith, Norman J., Gardner, Sarah A., Walker, Samuel P., Trainor, Patrick, Carter, Jane V., Bishop, Campbell, Sarojini, Harshini, O’Brien, Stephen J., Bhatnagar, Aruni, Polk, Hiram C., Galandiuk, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376008/
https://ncbi.nlm.nih.gov/pubmed/32699255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68018-x
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