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Unraveling Difficult Answers: From Genotype to Phenotype in Coronary Artery Disease

Genome-wide association studies (GWASs) have robustly found a correlation between coronary artery disease (CAD) and an intergenic region at locus 9p21.3. However, the mechanistic implication of this association is unknown. Recently in Cell, Lo Sardo et al. used hiPSC genome editing to demonstrate ho...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Magdy, Tarek, Burridge, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375859/
https://ncbi.nlm.nih.gov/pubmed/30735646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.01.008
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