Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome

Gene silencing using small-interfering RNA (siRNA) is a viable therapeutic approach; however, the lack of effective delivery systems limits its clinical translation. Herein, we doped conventional siRNA-liposomal formulations with gold nanoparticles to create “auroliposomes,” which significantly enha...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Hossen, Md. Nazir, Wang, Lin, Chinthalapally, Harisha R., Robertson, Joe D., Fung, Kar-Ming, Wilhelm, Stefan, Bieniasz, Magdalena, Bhattacharya, Resham, Mukherjee, Priyabrata
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375829/
https://ncbi.nlm.nih.gov/pubmed/32743073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba5379
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