HIP (HPA-screening in pregnancy) study: protocol of a nationwide, prospective and observational study to assess incidence and natural history of fetal/neonatal alloimmune thrombocytopenia and identifying pregnancies at risk

INTRODUCTION: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) may lead to severe fetal or neonatal bleeding and/or perinatal death. Maternal alloantibodies, targeted against fetal human platelet antigens (HPAs), can result thrombocytopenia and bleeding complications. In pregnancies with known...

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Veröffentlicht in:BMJ Open
Hauptverfasser: Winkelhorst, Dian, de Vos, Thijs W, Kamphuis, Marije M, Porcelijn, Leendert, Lopriore, Enrico, Oepkes, Dick, van der Schoot, C Ellen, de Haas, Masja
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Obstetrics and Gynaecology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375633/
https://ncbi.nlm.nih.gov/pubmed/32690731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-034071
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