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Enhanced cytotoxicity against solid tumors by bispecific antibody-armed CD19 CAR T cells: a proof-of-concept study
PURPOSE: Although adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells has shown durable clinical efficacy in patients with CD19(+) B-cell malignancies, the application of this approach to solid tumors is challenging. The goal of this proof-of-concept study was to investigat...
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| Publicado no: | J Cancer Res Clin Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375514/ https://ncbi.nlm.nih.gov/pubmed/32449004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-020-03260-4 |
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