A Genetically Engineered Rotavirus NSP2 Phosphorylation Mutant Impaired in Viroplasm Formation and Replication Shows an Early Interaction between vNSP2 and Cellular Lipid Droplets

Many RNA viruses replicate in cytoplasmic compartments (virus factories or viroplasms) composed of viral and cellular proteins, but the mechanisms required for their formation remain largely unknown. Rotavirus (RV) replication in viroplasms requires interactions between virus nonstructural proteins...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Criglar, Jeanette M., Crawford, Sue E., Zhao, Boyang, Smith, Hunter G., Stossi, Fabio, Estes, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375380/
https://ncbi.nlm.nih.gov/pubmed/32461314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00972-20
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