Overrunning in clinical trials: some thoughts from a methodological review

BACKGROUND: In sequential and adaptive trials, the delay that happens after the trial is stopped, by a predetermined stopping criterion, takes the name of overrunning. Overrunning consists of extra data, collected by investigators while awaiting results of the interim analysis (IA). The inclusion of...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Baldi, Ileana, Azzolina, Danila, Soriani, Nicola, Barbetta, Beatrice, Vaghi, Paola, Giacovelli, Giampaolo, Berchialla, Paola, Gregori, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374901/
https://ncbi.nlm.nih.gov/pubmed/32693832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04526-5
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