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MiR-221/SIRT1/Nrf2 signal axis regulates high glucose induced apoptosis in human retinal microvascular endothelial cells

BACKGROUND: Diabetic retinopathy (DR) is a serious symptom associated with diabetes and could cause much suffer to patients. MiR-221, SIRT1 and Nrf2 were associated with apoptosis and proliferation and their expression were altered in DR patients. However, their roles and regulatory mechanisms in hu...

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Bibliografske podrobnosti
izdano v:BMC Ophthalmol
Main Authors: Chen, Bin, Wu, Li, Cao, Ting, Zheng, Hong-Mei, He, Tao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374880/
https://ncbi.nlm.nih.gov/pubmed/32698791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-020-01559-x
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