Exploiting phage receptor binding proteins to enable endolysins to kill Gram-negative bacteria

Bacteriophage-encoded endolysins degrading the bacterial peptidoglycan are promising antibacterials for combating antibiotic-resistant bacteria. However, endolysins have limited use against Gram-negative bacteria, since the outer membrane prevents access to the peptidoglycan. Here, we present Innoly...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zampara, Athina, Sørensen, Martine C. Holst, Grimon, Dennis, Antenucci, Fabio, Vitt, Amira Ruslanovna, Bortolaia, Valeria, Briers, Yves, Brøndsted, Lone
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374709/
https://ncbi.nlm.nih.gov/pubmed/32694655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68983-3
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