Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) arises from cholangiocytes in the intrahepatic bile duct and is the second most common type of liver cancer. Cholangiocytes express both oestrogen receptor-α and -β, and oestrogens positively modulate cholangiocyte proliferation. Studies in women and...

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Publié dans:Br J Cancer
Auteurs principaux: Petrick, Jessica L., McMenamin, Úna C., Zhang, Xuehong, Zeleniuch-Jacquotte, Anne, Wactawski-Wende, Jean, Simon, Tracey G., Sinha, Rashmi, Sesso, Howard D., Schairer, Catherine, Rosenberg, Lynn, Rohan, Thomas E., Robien, Kim, Purdue, Mark P., Poynter, Jenny N., Palmer, Julie R., Lu, Yunxia, Linet, Martha S., Liao, Linda M., Lee, I-Min, Koshiol, Jill, Kitahara, Cari M., Kirsh, Victoria A., Hofmann, Jonathan N., Graubard, Barry I., Giovannucci, Edward, Gaziano, J. Michael, Gapstur, Susan M., Freedman, Neal D., Florio, Andrea A., Chong, Dawn Q., Chen, Yu, Chan, Andrew T., Buring, Julie E., Freeman, Laura E. Beane, Bea, Jennifer W., Cardwell, Christopher R., Campbell, Peter T., McGlynn, Katherine A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374167/
https://ncbi.nlm.nih.gov/pubmed/32376888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0835-5
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