Genomic Analysis Identifies Mutations Concerning Drug-Resistance and Beijing Genotype in Multidrug-Resistant Mycobacterium tuberculosis Isolated From China

Development of modern genomics provides us an effective method to understand the molecular mechanism of drug resistance and diagnose drug-resistant Mycobacterium tuberculosis. In this study, mutations in 18 genes or intergenic regions acquired by whole-genome sequencing (WGS) of 183 clinical M. tube...

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Vydáno v:Front Microbiol
Hlavní autoři: Wan, Li, Liu, Haican, Li, Machao, Jiang, Yi, Zhao, Xiuqin, Liu, Zhiguang, Wan, Kanglin, Li, Guilian, Guan, Cha-xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373740/
https://ncbi.nlm.nih.gov/pubmed/32760357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01444
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