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Pharmacological inhibition of lipid peroxidative damage by the 21-aminosteroid U-74389G improves cortical mitochondrial function following traumatic brain injury in young adult male rats.
The 21-aminosteroid (“lazaroid”) U-74389G (U74), an inhibitor of lipid peroxidation (LP), was used to protect mitochondrial function following TBI in young adult male rats. The animals received a severe (2.2 mm) controlled cortical impact-TBI. U74 was administered intravenous at 15 min and 2 hrs pos...
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| Wydane w: | Neuropharmacology |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7373435/ https://ncbi.nlm.nih.gov/pubmed/32142792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108023 |
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