Clustered gamma-protocadherins regulate cortical interneuron programmed cell death

Cortical function critically depends on inhibitory/excitatory balance. Cortical inhibitory interneurons (cINs) are born in the ventral forebrain and migrate into cortex, where their numbers are adjusted by programmed cell death. Here, we show that loss of clustered gamma protocadherins (Pcdhg), but...

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Pubblicato in:eLife
Autori principali: Mancia Leon, Walter R, Spatazza, Julien, Rakela, Benjamin, Chatterjee, Ankita, Pande, Viraj, Maniatis, Tom, Hasenstaub, Andrea R, Stryker, Michael P, Alvarez-Buylla, Arturo
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373431/
https://ncbi.nlm.nih.gov/pubmed/32633719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55374
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