New insights on human essential genes based on integrated analysis and the construction of the HEGIAP web-based platform

Essential genes are those whose loss of function compromises organism viability or results in profound loss of fitness. Recent gene-editing technologies have provided new opportunities to characterize essential genes. Here, we present an integrated analysis that comprehensively and systematically el...

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Publicat a:Brief Bioinform
Autors principals: Chen, Hebing, Zhang, Zhuo, Jiang, Shuai, Li, Ruijiang, Li, Wanying, Zhao, Chenghui, Hong, Hao, Huang, Xin, Li, Hao, Bo, Xiaochen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Problem Solving Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373178/
https://ncbi.nlm.nih.gov/pubmed/31504171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbz072
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